Who should benzodiazepines be avoided in due to increased risks?

Benzodiazepines should be avoided primarily in older adults and patients with a history of alcohol or drug dependence due to the heightened risks associated with their use in these groups. In older adults, benzodiazepines can increase the likelihood of cognitive impairment, falls, and other adverse effects. This population may already have diminished metabolic function and increased sensitivity to medications, making them more susceptible to the sedative effects of benzodiazepines, which can lead to serious consequences such as fractures or increased confusion.

For individuals with a history of alcohol or drug dependence, using benzodiazepines can pose significant risks as they may have a higher propensity for misuse or developing dependence on these medications. The potential for interaction with substances, along with the risks of addiction and withdrawal symptoms, makes it crucial to avoid prescribing benzodiazepines to this group.

Understanding these risks helps clinicians make safer choices in medication management, especially in vulnerable populations. The other patient populations mentioned do not carry the same level of concern regarding the risks associated with benzodiazepine use.