Which of the following non-BZ sedatives is known for its rapid onset of action?

Both Sonata (zaleplon) and Ambien (zolpidem) are known for their rapid onset of action when used as non-benzodiazepine sedatives. Sonata has a very short half-life, often allowing patients to fall asleep quickly, making it particularly effective for those who have difficulty initiating sleep. Similarly, Ambien is designed to help individuals who struggle with sleep onset and typically takes effect rapidly as well.

This rapid action is due to their pharmacokinetic profiles, which favor quick absorption and onset of sedative effects. In clinical contexts, these medications are frequently chosen for their ability to help patients achieve sleep quickly without the prolonged sedative effects sometimes associated with other longer-acting agents. Therefore, the combination of both Sonata and Ambien being effective in this regard justifies the selection of this answer.