Which herbal supplement is often used to treat mild to moderate depression?

St. John's Wort is widely recognized for its efficacy in treating mild to moderate depression. This herbal supplement contains active compounds such as hypericin and hyperforin, which are thought to influence neurotransmitter activity in the brain, particularly serotonin, dopamine, and norepinephrine. Research has shown that St. John's Wort can be as effective as certain prescription antidepressants for individuals suffering from mild to moderate depressive symptoms, making it a popular alternative treatment option.

In contrast, Ginkgo biloba is primarily used for cognitive enhancement and improving memory, rather than as a treatment for depression. Valerian root is mostly utilized for its sedative properties and is often used to alleviate insomnia or anxiety rather than depressive symptoms. Chamomile, while beneficial for anxiety and relaxation, does not have strong evidence supporting its use specifically for depression. Thus, St. John's Wort stands out as the herbal option most prominently associated with antidepressant effects.