What is a potential consequence of abruptly discontinuing benzodiazepines?

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Abruptly discontinuing benzodiazepines can lead to withdrawal symptoms, which can include seizures. This is primarily due to the physiological dependence that can develop with the chronic use of these medications. Benzodiazepines work by enhancing the effects of the neurotransmitter GABA, leading to increased inhibitory action in the brain. When these medications are stopped suddenly, the central nervous system can react adversely due to the lack of GABA's calming effects. Withdrawal symptoms may also encompass anxiety, agitation, insomnia, and in severe cases, life-threatening symptoms like seizures. Therefore, it is important for individuals to taper off benzodiazepines under medical supervision to minimize these risks.

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