Which side effect is commonly associated with the use of BZs?

Impaired coordination is a well-documented side effect of benzodiazepines (BZs). These medications, which are primarily used to treat anxiety, insomnia, and other related disorders, act as central nervous system depressants. By enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA), they can lead to sedation, muscle relaxation, and decreased motor function. This sedative effect can result in impaired coordination, which is particularly concerning in activities that require precise motor skills, such as driving or operating machinery.

Additionally, this impairment can vary based on dosage, individual sensitivity, and the duration of use, with higher doses and long-term usage typically exacerbating coordination issues. Therefore, monitoring for this side effect is crucial, especially in environments where safety and coordination are paramount.